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Last updated: 2017/8/20
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TRAF1 polyclonal antibody

  • Catalog # : PAB0274
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of TRAF1.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 1-22 of human TRAF1.
  • Sequence:
  • MASSSGSSPRPAPDENEFPFG
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In serum (0.05% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of TRAF1 in normal human tissues. Using TRAF1 polyclonal antibody (Cat # PAB0274) at 1 : 2000. TRAF1 is observed at 50-50 KDa. Additional bands of lower molecular weight were seen in some cases, and may represent TRAF1 degradation fragments.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Formalin-fixed, paraffin-embedded human lymphoma tissue section stained for TRAF1 expression. Using TRAF1 polyclonal antibody (Cat # PAB0274) at 1 : 2000. Hematoxylin-eosin counterstain. A1 is a higher magnification of A.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Formalin-fixed, paraffin-embedded human tissue sections stained for TRAF1 expression. Using TRAF1 polyclonal antibody (Cat # PAB0274) at 1 : 2000. Hematoxylin-eosin counterstain. A, A1 : Formalin-fixed, paraffin-embedded human lymphoma tissue section stained for TRAF1 expression. Using TRAF1 polyclonal antibody (Cat # PAB0274) at 1 : 2000. Hematoxylin-eosin counterstain. A, Hodgkin's Disease, the Reed-Sternberg cells are positive for TRAF1 expression. B, lymph node, dendritic-like cells are positive for TRAF1 expression. A1 and B1 are higher magnifications from A and B, respectively. .
  • Immunoprecipitation
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 7185
  • Gene Name:
  • TRAF1
  • Gene Alias:
  • EBI6,MGC:10353
  • Gene Description:
  • TNF receptor-associated factor 1
  • Gene Summary:
  • The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. [provided by RefSeq
  • Other Designations:
  • Epstein-Bar virus-induced protein 6,OTTHUMP00000022000
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