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Last updated: 2016/12/4
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NLRP2 polyclonal antibody

  • Catalog # : PAB0267
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of NLRP2.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 144-159 of human NLRP2.
  • Sequence:
  • LGKEVFKGKKPDKDNR
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In serum (0.05% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of NLRP2 in differentiated THP-1 cells following IFN (interferon) g stimulation using NLRP2 polyclonal antibody (Cat # PAB0267) at 1 : 2000. TPA-differentiated THP-1 cells were cultured with 1000 units of IFNg for 0-24 hours as described in Bruey et al, 2004. Culturing differentiated THP-1 with IFNg resulted in transient elevations in NLRP2 expression which peaked at 4-8 h after INFg treatment.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Gene Information
  • Gene Name:
  • NLRP2
  • Gene Alias:
  • CLR19.9,FLJ20510,NALP2,NBS1,PAN1,PYPAF2
  • Gene Description:
  • NLR family, pyrin domain containing 2
  • Gene Summary:
  • NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1; MIM 147678) by Toll-like receptors (see TLR4; MIM 603030). They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM
  • Other Designations:
  • NACHT, LRR and PYD containing protein 2,NACHT, leucine rich repeat and PYD containing 2,PYRIN-Containing APAF1-like,nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 2
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