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Last updated: 2018/1/14
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NOD2 polyclonal antibody

  • Catalog # : PAB0265
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of NOD2.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 582-600 of human NOD2/CARD15.
  • Sequence:
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In serum (0.05% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of NOD2. Using NOD2 polyclonal antibody (Cat # PAB0265) at 1 : 2000. 30 ug total protein was loaded per lane. Samples from human tumor cell lines : PPC-1 (prostate carcinoma) , NCI-H226 and NCI-H332M (lung carcinoma) , SF-268 (glioblastoma) , UO-31 and A498 (renal/kidney carcinoma) , SK-MEL-5 and SK-MEL-28 (melanoma) , and MCF-7 (breast carcinoma) . Lymphoma is from a cell line generated from a tumor growing in nude mice following injection of primary human lymphoma cells.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Formalin-fixed, paraffin-embedded normal human colon stained for NOD2 expression. Using NOD2 polyclonal antibody (Cat # PAB0265) at 1 : 2000. A, tissue core from a colon tissue microarray. A1, high magnification of A. Hematoxylin-eosin counterstain.
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Gene Information
  • Gene Name:
  • NOD2
  • Gene Alias:
  • Gene Description:
  • nucleotide-binding oligomerization domain containing 2
  • Gene Summary:
  • This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. [provided by RefSeq
  • Other Designations:
  • NLR family, CARD domain containing 2,NOD-like receptor C2,OTTHUMP00000164224,caspase recruitment domain family, member 15,caspase recruitment domain protein 15,inflammatory bowel disease protein 1,nucleotide-binding oligomerization domain 2,nucleotide-bin
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