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Last updated: 2017/12/10
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NLRP1 polyclonal antibody

  • Catalog # : PAB0261
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of NLRP1.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 1058-1077 of human NLRP1.
  • Sequence:
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In serum (0.05% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Formalin-fixed, paraffin-embedded normal human bone marrow stained for NLRP1 (CARD7/NAP) using NLRP1 polyclonal antibody (Cat # PAB0261) at 1 : 2000. Hematoxylin-eosin counterstain. Staining is seen in differentiated granulocytes.
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Immunoprecipitation
  • Immunoprecipitation/Western blot analysis of NLRP1 (NAC/CARD7) in Jurkat cells. Using NLRP1 polyclonal antibody (Cat # PAB0262) and NLRP1 polyclonal antibody (Cat # PAB0261). Cell lysates were immunoprecipitated with NLRP1 polyclonal antibody (Cat # PAB0262) (2 ul/one million cells) and western blotted with NLRP1 polyclonal antibody (Cat # PAB0261) at 1 : 2000.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunohistochemistry (Frozen sections)
  • Gene Information
  • Gene Name:
  • NLRP1
  • Gene Alias:
  • Gene Description:
  • NLR family, pyrin domain containing 1
  • Gene Summary:
  • This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq
  • Other Designations:
  • NACHT, LRR and PYD containing protein 1,NACHT, leucine rich repeat and PYD (pyrin domain) containing 1,NACHT, leucine rich repeat and PYD containing 1,caspase recruitment domain protein 7,death effector filament-forming Ced-4-like apoptosis protein,nucleo
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