TANK polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of TANK expression in formalin-fixed, paraffin-embedded normal human colon. Using TANK polyclonal antibody (Cat # PAB0259) at 1 : 2000. A-A3, low and high magnification images. Hematoxylin-eosin counterstain.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TANK.
Immunogen
A synthetic peptide corresponding to amino acids 346-367 of human TANK/I-TRAF.
Sequence
DPSDAPFPSLDSPGKAIRGPQQ
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In serum (0.05% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of TANK expression in formalin-fixed, paraffin-embedded normal human colon. Using TANK polyclonal antibody (Cat # PAB0259) at 1 : 2000. A-A3, low and high magnification images. Hematoxylin-eosin counterstain.Immunohistochemistry (Frozen sections)
Immunoprecipitation
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Gene Info — TANK
Entrez GeneID
10010Gene Name
TANK
Gene Alias
I-TRAF, TRAF2
Gene Description
TRAF family member-associated NFKB activator
Omim ID
603893Gene Ontology
HyperlinkGene Summary
The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
TRAF family member-associated NF-KAPPA-B activator|TRAF interacting protein TANK
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Interactome
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Disease
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