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Last updated: 2016/12/4
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NLRC4 polyclonal antibody

  • Catalog # : PAB0258
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of NLRC4.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 637-654 of human NLRC4.
  • Sequence:
  • EEAPETYIPSRAVSLFFN
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In serum (0.05% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Gene Information
  • Gene Name:
  • NLRC4
  • Gene Alias:
  • CARD12,CLAN,CLAN1,CLANA,CLANB,CLANC,CLAND,CLR2.1,IPAF
  • Gene Description:
  • NLR family, CARD domain containing 4
  • Gene Summary:
  • In C. elegans, Ced4 binds and activates Ced3, an apoptotic initiator caspase, via caspase-associated recruitment domains (CARDs). Human Ced4 homologs include APAF1 (MIM 602233), NOD1/CARD4 (MIM 605980), and NOD2/CARD15 (MIM 605956). These proteins have at least 1 N-terminal CARD domain followed by a centrally located nucleotide-binding domain (NBD or NACHT) and a C-terminal regulatory domain, found only in mammals, that contains either WD40 repeats or leucine-rich repeats (LRRs). CARD12 is a member of the Ced4 family and can induce apoptosis.[supplied by OMIM
  • Other Designations:
  • ICE-protease activating factor,NOD-like receptor C4,caspase recruitment domain family, member 12,caspase recruitment domain protein 12,nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 4
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