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Last updated: 2016/11/27
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BIRC3 polyclonal antibody

  • Catalog # : PAB0253
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of BIRC3.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 532-549 of human BIRC3.
  • Sequence:
  • KYIPTEDVSDLPVEEQLR
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In serum (0.05% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of BIRC3 in various cancer cell lines. Using BIRC3 polyclonal antibody (Cat # PAB0253) at 1 : 2000.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of BIRC3 in paraffin-embedded formalin-fixed human mammary gland (female breast) using BIRC3 polyclonal antibody (Cat # PAB0253) at 1:2000.
    A, normal breast tissue.
    B, ductal carcinoma in situ (DCIS).
    C. invasive neoplasia.
    BIRC3 expressed increased sucessively with tumor progression.
    Hematoxylin-eosin counterstain.
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 330
  • Gene Name:
  • BIRC3
  • Gene Alias:
  • AIP1,API2,CIAP2,HAIP1,HIAP1,MALT2,MIHC,RNF49
  • Gene Description:
  • baculoviral IAP repeat-containing 3
  • Gene Summary:
  • The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq
  • Other Designations:
  • TNFR2-TRAF signaling complex protein,apoptosis inhibitor 2,baculoviral IAP repeat-containing protein 3,inhibitor of apoptosis protein 1,mammalian IAP homolog C
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