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Last updated: 2017/11/19
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BIRC2 polyclonal antibody

  • Catalog # : PAB0252
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against full length recombinant BIRC2.
  • Immunogen:
  • Recombinant protein corresponding to full length human BIRC2.
  • Host:
  • Rabbit
  • Reactivity:
  • Dog, Gerbils, Human, Mouse, Rat
  • Form:
  • Liquid
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In serum (0.05% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of BIRC2 in human prostate. Using BIRC2 polyclonal antibody (Cat # PAB0252) at 1 : 1000. PBH (benign prostate hyperplasia) , PIN (prostate intraepithelial neoplasia) . Elevated levels of BIRC2 were seen in certain cases of BPH/PIN and prostate cancer compared to normal prostate.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of BIRC2 in formalin-fixed, paraffin-embedded human prostate. Using BIRC2 polyclonal antibody (Cat # PAB0252) at 1 : 2000. A, normal prostate. B, prostate intraepithelial neoplasia (PIN) . PIN is a premalignant proliferation arising within the prostate. C, prostate cancer. Hematoxylin-eosin counterstain. Increased BIRC2 expression is PIN and in prostate cancer compared to normal prostate.
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 329
  • Gene Name:
  • BIRC2
  • Gene Alias:
  • API1,HIAP2,Hiap-2,MIHB,RNF48,cIAP1
  • Gene Description:
  • baculoviral IAP repeat-containing 2
  • Gene Summary:
  • The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. [provided by RefSeq
  • Other Designations:
  • NFR2-TRAF signalling complex protein,apoptosis inhibitor 1,baculoviral IAP repeat-containing protein 2
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