TLR1 polyclonal antibody
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More Files
- More Functions
Western Blot
Western blot analysis of TLR1 in Ramos (A), Raw (B), and (C) TLR1 transfected cell lysate using TLR1 polyclonal antibody (Cat # PAB0215) at 2 ug/mL .
Flow Cytometry
Intracellular flow cytometric analysis of TLR1 in human PBMCs (monocyte-gated) using TLR1 polyclonal antibody (Cat # PAB0215) at 0.5 ug/10^6 cells. Shaded histogram represents cells without antibody, Green represents isotype control, red represents TLR1 antibody.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TLR1.
Immunogen
A synthetic peptide corresponding to amino acids 400-450 of human TLR1.
Host
Rabbit
Reactivity
Human, Rat
Form
Liquid
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.05% BSA, 0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of TLR1 in Ramos (A), Raw (B), and (C) TLR1 transfected cell lysate using TLR1 polyclonal antibody (Cat # PAB0215) at 2 ug/mL .Flow Cytometry
Intracellular flow cytometric analysis of TLR1 in human PBMCs (monocyte-gated) using TLR1 polyclonal antibody (Cat # PAB0215) at 0.5 ug/10^6 cells. Shaded histogram represents cells without antibody, Green represents isotype control, red represents TLR1 antibody. -
Gene Info — TLR1
Entrez GeneID
7096Gene Name
TLR1
Gene Alias
CD281, DKFZp547I0610, DKFZp564I0682, KIAA0012, MGC104956, MGC126311, MGC126312, TIL, rsc786
Gene Description
toll-like receptor 1
Omim ID
601194Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene. [provided by RefSeq
Other Designations
Toll/interleukin-1 receptor-like
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Interactome
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Pathway
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Disease
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Publication Reference
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Changes in the expression of the toll-like receptor system in the aging rat kidneys.
Xi Y, Shao F, Bai XY, Cai G, Lv Y, Chen X.
PLoS One 2014 May; 9(5):e96351.
Application：WB-Ti, Rat, Renal.
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Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils.
Wong CK, Cheung PF, Ip WK, Lam CW.
American Journal of Respiratory Cell and Molecular Biology 2007 Mar; 37(1):85.
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Members of the Toll-like receptor family of innate immunity pattern-recognition receptors are abundant in the male rat reproductive tract.
Palladino MA, Johnson TA, Gupta R, Chapman JL, Ojha P.
Biology of Reproduction 2007 Jun; 76(6):958.
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Changes in the expression of the toll-like receptor system in the aging rat kidneys.
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