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Last updated: 2016/10/23
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SOCS1 polyclonal antibody

  • Catalog # : PAB0214
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of SOCS1.
  • Immunogen:
  • A synthetic peptide corresponding to human SOCS1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% BSA, 0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of SOCS1. Using SOCS1 polyclonal antibody (Cat # PAB0214) at 1 : 1000 dilution against 15 ug/lane of Ramos (A) and Raw (B) cell lysate.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 8651
  • Gene Name:
  • SOCS1
  • Gene Alias:
  • Gene Description:
  • suppressor of cytokine signaling 1
  • Gene Summary:
  • This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq
  • Other Designations:
  • JAK binding protein,STAT induced SH3 protein 1,Tec-interacting protein 3,cytokine-inducible SH2 protein 1
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