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TMEM123 polyclonal antibody

  • Catalog # : PAB0204
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of TMEM123.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 173-188 of human TMEM123.
  • Sequence:
  • SRRGIRYRTIDEHDAI
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.2% gelatin, 0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of TMEM123. Using TMEM123 polyclonal antibody (Cat # PAB0204) at 2 ug/mL dilution against 20 ug/lane of HL-60 cell lysate.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • TMEM123
  • Gene Alias:
  • KCT3,PORIMIN,PORMIN
  • Gene Description:
  • transmembrane protein 123
  • Gene Summary:
  • This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. [provided by RefSeq
  • Other Designations:
  • keratinocytes associated transmembrane protein 3,pro oncosis receptor inducing membrane injury,pro-oncosis receptor inducing membrane injury,serine/threonine-rich receptor
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