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Last updated: 2016/10/23
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PYCARD polyclonal antibody

  • Catalog # : PAB0198
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of PYCARD.
  • Immunogen:
  • A mixture of synthetic peptides corresponding to amino acids 31-46 and 94-110 of human PYCARD.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.2% gelatin, 0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis for PYCARD using PYCARD polyclonal antibody (Cat # PAB0198) at 2 ug/mL against 10 ug/lane of A-549 cell lysate.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • Gene Alias:
  • Gene Description:
  • PYD and CARD domain containing
  • Gene Summary:
  • This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • apoptosis-associated speck-like protein containing a CARD,caspase recruitment domain protein 5,target of methylation-induced silencing-1
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