HDAC6 polyclonal antibody
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More Files
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Western Blot (Cell lysate)
Western blot analysis of HDAC6 in NIH/3T3 cell lysate with HDAC6 polyclonal antibody (Cat # PAB0183) .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of HDAC6.
Immunogen
A synthetic peptide corresponding to amino acids 1-16 of human HDAC6.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.05% BSA, 0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
ChIP
Western Blot (Cell lysate)
Western blot analysis of HDAC6 in NIH/3T3 cell lysate with HDAC6 polyclonal antibody (Cat # PAB0183) .Immunoprecipitation
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Gene Info — HDAC6
Entrez GeneID
10013Gene Name
HDAC6
Gene Alias
FLJ16239, HD6, JM21
Gene Description
histone deacetylase 6
Omim ID
300272Gene Ontology
HyperlinkGene Summary
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq
Other Designations
OTTHUMP00000032398
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Interactome
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Disease
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Publication Reference
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Direct p53 transcriptional repression: in vivo analysis of CCAAT-containing G2/M promoters.
Imbriano C, Gurtner A, Cocchiarella F, Di Agostino S, Basile V, Gostissa M, Dobbelstein M, Del Sal G, Piaggio G, Mantovani R.
Molecular and Cellular Biology 2005 May; 25(9):3737.
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Direct p53 transcriptional repression: in vivo analysis of CCAAT-containing G2/M promoters.
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