Product Browser

Last updated: 2017/8/20
  • Related Product Showcase

Product Compare

Product Compare Cancel Click this icon to add products to compare list. Select up to 10 products.

Quick Order (Tutorial)

Input Catalog #,
place order here!
Catalog # :
  • Where to buy
  • Choose your location

CCR1 polyclonal antibody

  • Catalog # : PAB0176
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CCR1.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 339-350 of human CCR1.
  • Sequence:
  • VSSTSPSTGEHE
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Recommend Usage:
  • Flow Cytometry (5-10 ul)
    Western Blot (1-3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.2% gelatin, 0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of 10 ug of total cell lysate from A-375 cells with CCR1 polyclonal antibody (Cat # PAB0176) at 2 ug/mL dilution.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-Fixed Paraffin-Embedded Sections) staining of human spleen with CCR1 polyclonal antibody (Cat # PAB0176).
  • Flow Cytometry
  • Flow Cytometry
  • Left image : Surface staining of mouse primary epidermal cells (B-6 mice, 30 wks) with CL 11-PE, CD11c PE-Cy5, and CCR1 polyclonal antibody (Cat # PAB0176) with CY5 goat anti rabbit secondary. Right image : CD11c+ CL II+ cells (Langerans), stained with rabbit isotype control (shaded histogram) were analyzed for CCR1 at 5 uL (blue histogram) and 10 uL (Green histogram). Data kindly provided by Corey Parlet, University of Iowa.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1230
  • Gene Name:
  • CCR1
  • Gene Alias:
  • CD191,CKR-1,CKR1,CMKBR1,HM145,MIP1aR,SCYAR1
  • Gene Description:
  • chemokine (C-C motif) receptor 1
  • Gene Summary:
  • This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq
  • Other Designations:
  • RANTES receptor
  • RSS
  • YouTube
  • Linkedin
  • Facebook