PSENEN polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis in rat brain homogenate (15 ug). Overnight incubation PVDF membrane with PSENEN polyclonal antibody (Cat # PAB0141) (15 ug/mL) in PBS containing 1% PBS. Horesradish peroxidase-conjugated anti-rabbit (0.5 ug/mL ; GE-Biosciences) was used for detection.
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide conjugated to KLH.
Immunogen
A synthetic peptide (conjugated to KLH) corresponding to N-terminus 11 amino acids of human PSENEN.
Host
Rabbit
Reactivity
Hamster, Human, Mouse
Form
Lyophilized
Recommend Usage
Western Blot (5-10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from purified antibody
Storage Instruction
Store at -20°C on dry atmosphere.
After reconstitution with sterile water, store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Tissue lysate)
Western blot analysis in rat brain homogenate (15 ug). Overnight incubation PVDF membrane with PSENEN polyclonal antibody (Cat # PAB0141) (15 ug/mL) in PBS containing 1% PBS. Horesradish peroxidase-conjugated anti-rabbit (0.5 ug/mL ; GE-Biosciences) was used for detection. -
Gene Info — PSENEN
Entrez GeneID
55851Gene Name
PSENEN
Gene Alias
MDS033, MSTP064, PEN-2, PEN2
Gene Description
presenilin enhancer 2 homolog (C. elegans)
Omim ID
607632Gene Ontology
HyperlinkGene Summary
Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. [provided by RefSeq
Other Designations
hematopoietic stem/progenitor cells protein MDS033|presenilin enhancer 2
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com