CCL1 (Human) Recombinant Protein
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Specification
Product Description
Human CCL1 (P22362, 23 a.a. - 96 a.a.) partial recombinant protein expressed in Escherichia coli.
Sequence
SKSMQVPFSRCCFSFAEQEIPLRAILCYRNTSSICSNEGLIFKLKRGKEACALDTVGWVQRHRKMLRHCPSKRK
Host
Escherichia coli
Theoretical MW (kDa)
8.5
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
> 99.0% by SDS-PAGE
Activity
The Biological activity is 10 - 100 ng/mL, was determined by the ability to chemoattract human T cells, corresponding to a specific activity of 10000 - 100000 IU/mg.
Recommend Usage
Biological Activity
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from sterile distilled Water is > 100 ug/mL
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — CCL1
Entrez GeneID
6346Protein Accession#
P22362Gene Name
CCL1
Gene Alias
I-309, P500, SCYA1, SISe, TCA3
Gene Description
chemokine (C-C motif) ligand 1
Omim ID
182281Gene Ontology
HyperlinkGene Summary
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine receptor CCR8. [provided by RefSeq
Other Designations
T lymphocyte-secreted protein I-309|inflammatory cytokine I-309|small inducible cytokine A1|small inducible cytokine A1 (I-309, homologous to mouse Tca-3)
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Interactome
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Pathway
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Disease
- Adenocarcinoma
- Arthritis
- Asthma
- Atherosclerosis
- Birth Weight
- Breast cancer
- Breast Neoplasms
- Bronchiolitis
- Colon cancer
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