EPOR (Human) Recombinant Protein
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Specification
Product Description
Human EPOR partial recombinant protein with His tag in C-terminus expressed in Baculovirus cells.
Sequence
APPPNLPDPKFESKAALLAARGPEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRYEVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPSDLDPHHHHHH
Host
Viruses
Theoretical MW (kDa)
25.6
Form
Liquid
Preparation Method
Baculovirus expression system
Purification
Chromatography
Purity
> 95% as determined by SDS-PAGE.
Storage Buffer
In PBS, pH 7.4 (10% glycerol).
Storage Instruction
Stored at 4°C for 2-4 weeks, should be stored at -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid repeated freeze/thaw cycles. -
Applications
SDS-PAGE
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Gene Info — EPOR
Entrez GeneID
2057Protein Accession#
P19235Gene Name
EPOR
Gene Alias
MGC138358
Gene Description
erythropoietin receptor
Gene Ontology
HyperlinkGene Summary
The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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