SCYE1 (Human) Recombinant Protein
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Human SCYE1 (Q12904) recombinant protein expressed in Escherichia coli.
Sequence
SKPIDVSRLDLRIGCIITARKHPDADSLYVEEVDVGEIAPRTVVSGLVNHVPLEQMQNRMVILLCNLKPAKMRGVLSQAMVMCASSPEKIEILAPPNGSVPGDRITFDAFPGEPDKELNPKKKIWEQIQPDLHTNDECVATYKGVPFEVKGKGVCRAQTMSNSGIK.
Host
Escherichia coli
Theoretical MW (kDa)
18.3
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
> 98% by HPLC and SDS PAGE
Activity
Determined by the apoptotic effect on MCF-7 cells using a concentration of 20-30 ng/mL.
Storage Buffer
Lyophilized from 20mM sodium Phosphate buffer (pH 7.5) and 130mM sodium chloride.
Storage Instruction
Store at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles.
-
Applications
Functional Study
SDS-PAGE
-
Gene Info — SCYE1
Entrez GeneID
9255Protein Accession#
Q12904Gene Name
SCYE1
Gene Alias
AIMP1, EMAP2, EMAPII, p43
Gene Description
small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating)
Omim ID
603605Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. [provided by RefSeq
Other Designations
ARS-interacting multifunctional protein 1|OTTHUMP00000161878|endothelial monocyte-activating polypeptide 2|endothelial-monocyte activating polypeptide II|multisynthetase complex auxiliary component p43|small inducible cytokine subfamily E, member 1
-
Interactome
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com