ANGPTL3 (Human) Recombinant Protein
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Specification
Product Description
Human ANGPTL3 (Q9Y5C1, 243 a.a. - 460 a.a.) partial-length recombinant protein with His-tag at N-terminal expressed in Escherichia coli.
Amount
> 90% by SDS-PAGE
Sequence
MGSSHHHHHHSSGLVPRGSHMPAECTTIYNRGEHTSGMYAIRPSNSQVFHVYCDVISGSPWTLIQHRIDGSQNFNETWENYKYGFGRLDGEFWLGLEKIYSIVKQSNYVLRIELEDWKDNKHYIEYSFYLGNHETNYTLHLVAITGNVPNAIPENKDLVFSTWDHKAKGHFNCPEGYSGGWWWHDECGENNLNGKYNKPRAKSKPERRRGLSWKSQNGRLYSIKSTKMLIHPTDSESFE.
Host
Escherichia coli
Theoretical MW (kDa)
27.7
Form
Liquid
Preparation Method
Escherichia coli expression system
Storage Buffer
20mM Tris-HCl (pH8.0) and 10% glycerol.
Storage Instruction
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles. -
Applications
SDS-PAGE
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Gene Info — ANGPTL3
Entrez GeneID
27329Protein Accession#
Q9Y5C1Gene Name
ANGPTL3
Gene Alias
ANGPT5
Gene Description
angiopoietin-like 3
Omim ID
604774Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis. [provided by RefSeq
Other Designations
OTTHUMP00000010719|angiopoietin 5
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