INHBB (Human) Recombinant Protein
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Specification
Product Description
Human INHBB (P09529) recombinant protein with His-tag at N-terminal expressed in Nicotiana benthamiana expression system.
Amount
> 97% by SDS-PAGE
Sequence
HHHHHHHHHHGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECG
Host
Nicotiana benthamiana
Theoretical MW (kDa)
14
Form
Lyophilized
Preparation Method
Nicotiana benthamiana expression system
Storage Buffer
Lyophilized from 0.05M Tris-HCl buffer pH 7.4
Storage Instruction
Upon reconstitution should be stored at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
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Gene Info — INHBB
Entrez GeneID
3625Protein Accession#
P09529Gene Name
INHBB
Gene Alias
MGC157939
Gene Description
inhibin, beta B
Omim ID
147390Gene Ontology
HyperlinkGene Summary
The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. [provided by RefSeq
Other Designations
Inhibin, beta-2|activin AB beta polypeptide|inhibin beta B subunit
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