IGF2 (Human) Recombinant Protein
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Specification
Product Description
Human IGF2 (P01344, 24 a.a. - 180 a.a.) partial recombinant protein contains a C-terminal propeptide (E peptide) Arg92 to Lys180 expressed in HEK293 cells.
Sequence
AAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK
Host
Mammals
Theoretical MW (kDa)
25
Form
Lyophilized
Preparation Method
Mammalian cell (HEK293) expression system
Purity
> 90% by SDS-PAGE
Activity
The specific activity was determined by the dose-dependent stimulation of the proliferation of MCF-7 cells (human breast cancer cell line) and is typically 2-8 ng/mL.
Recommend Usage
Biological Activity
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
In sterile PBS containing 0.1% endotoxin-free recombinant HSA.
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — IGF2
Entrez GeneID
3481Protein Accession#
P01344Gene Name
IGF2
Gene Alias
C11orf43, FLJ22066, FLJ44734, INSIGF, pp9974
Gene Description
insulin-like growth factor 2 (somatomedin A)
Omim ID
147470Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the insulin family of polypeptide growth factors that is involved in development and growth. It is an imprinted gene and is expressed only from the paternally inherited allele. It is a candidate gene for eating disorders. There is a read-through, INS-IGF2, which aligns to this gene at the 3' region and to the upstream INS gene at the 5' region. Alternatively spliced transcript variants, encoding either the same or different isoform, have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000011012|OTTHUMP00000011015|OTTHUMP00000011018|OTTHUMP00000011157|insulin-like growth factor 2|insulin-like growth factor II|insulin-like growth factor type 2|putative insulin-like growth factor II associated protein|somatomedin A
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Interactome
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Disease
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