CSF2RA (Human) Recombinant Protein
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Specification
Product Description
Human CSF2RA (P15509, 20 a.a. - 320 a.a.) partial length recombinant protein with hIgG-His tag expressed in Baculovirus expression system.
Sequence
LIPEKSDLRTVAPASSLNVRFDSRTMNLSWDCQENTTFSKCFLTDKKNRVVEPRLSNNECSCTFREICLHEGVTFEVHVNTSQRGFQQKLLYPNSGREGTAAQNFSCFIYNADLMNCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLDNLSGLTSRNYFLVNGTSREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDVHRKNTQPGTENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRILNWSSWSEAIEFGSDDG
Host
Viruses
Theoretical MW (kDa)
35.9
Form
Liquid
Preparation Method
Baculovirus expression system
Purity
> 90% by SDS-PAGE
Endotoxin Level
< 1 EU per 1 ug of protein (determined by LAL method)
Activity
ED50 is < 10 ug/mL, measured by by the ability to inhibit proliferation using TF-1 human erythroleukemic cells.
Quality Control Testing
3 ug by SDS-PAGE under reducing condition and visualized by Coomassie blue stain.
Storage Buffer
In Phosphate-Buffer Saline pH 7.4 (10% glycerol)
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing.Note
Result of bioactivity analysis
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Applications
Functional Study
SDS-PAGE
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Gene Info — CSF2RA
Entrez GeneID
1438Protein Accession#
P15509Gene Name
CSF2RA
Gene Alias
CD116, CDw116, CSF2R, CSF2RAX, CSF2RAY, CSF2RX, CSF2RY, GM-CSF-R-alpha, GMCSFR, GMR, MGC3848, MGC4838
Gene Description
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble. [provided by RefSeq
Other Designations
CD116 antigen|GM-CSF receptor alpha subunit|OTTHUMP00000014504|OTTHUMP00000014505|OTTHUMP00000014917|OTTHUMP00000014918|colony stimulating factor 2 receptor alpha chain|colony stimulating factor 2 receptor alpha subunit|granulocyte-macrophage colony-stimu
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Interactome
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Pathway
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Disease
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