KLK13 (Human) Recombinant Protein
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Specifications
Product Description
Human KLK13 (Q9UKR3, 17 a.a. - 277 a.a.) partial length recombinant protein with His tag expressed in Baculovirus expression system.
Sequence
GGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETIRKYETQQQKWLKGPQ
Host
Viruses
Theoretical MW (kDa)
29.7
Form
Liquid
Preparation Method
Baculovirus expression system
Purity
> 90% by SDS-PAGE
Endotoxin Level
< 1 EU per 1 ug of protein (determined by LAL method)
Activity
Specific activity is > 8000 pmol/min/ug, one unit will hydrolyze 1.0 pmole of BAEE to Na-Benzoyl-L-arginine per minute at pH 8.0 at 25°C.
Quality Control Testing
3 ug by SDS-PAGE under reducing condition and visualized by Coomassie blue stain.
Storage Buffer
In Phosphate-Buffer Saline pH 7.4 (10% glycerol)
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — KLK13
Entrez GeneID
26085Protein Accession#
Q9UKR3Gene Name
KLK13
Gene Alias
DKFZp586J1923, KLK-L4, KLKL4
Gene Description
kallikrein-related peptidase 13
Omim ID
605505Gene Ontology
HyperlinkGene Summary
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq
Other Designations
kallikrein 13|kallikrein-like gene 4
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Interactomes
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Diseases
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