IL17RB (Human) Recombinant Protein
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Specification
Product Description
Human IL17RB (Q9NRM6, 18 a.a. - 292 a.a.) partial recombinant protein with higG-His tag expressed in Baculovirus.
Sequence
REPTVQCGSETGPSPEWMLQHDLIPGDLRDLRVEPVTTSVATGDYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWTFSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSPGCLDHIMKYKKKCVKAGSLWDPNITACKKNEETVEVNFTTTPLGNRYMALIQHSTIIGFSQVFEPHQKKQTRASVVIPVTGDSEGATVQLTPYFPTCGSDCIRHKGTVVLCPQTGVPFPLDNNKSKPGGWLP
Host
Viruses
Theoretical MW (kDa)
57.3
Form
Liquid
Preparation Method
Baculovirus expression system
Purity
> 85% as analyzed by SDS-PAGE.
Endotoxin Level
< 1 EU/ug of protein by the LAL method.
Activity
ED50 < 2 ug/mL, measured by the binding ability in a functional ELISA with Human IL25
Quality Control Testing
SDS-PAGE Stained with Coomassie Blue.
SDS-PAGE analysis of IL17RB (Human) Recombinant Protein.
Recommend Usage
Biological Activity
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (10% glycerol)
Storage Instruction
Store at 4°C for 1 week. For long term storage store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing.Note
Result of activity analysis
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Applications
Functional Study
SDS-PAGE
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Gene Info — IL17RB
Entrez GeneID
55540Protein Accession#
Q9NRM6Gene Name
IL17RB
Gene Alias
CRL4, EVI27, IL17BR, IL17RH1, MGC5245
Gene Description
interleukin 17 receptor B
Omim ID
605458Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq
Other Designations
IL-17B receptor|cytokine receptor CRL4|interleukin 17 receptor homolog 1|interleukin 17B receptor
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