BMP8B (Human) Recombinant Protein
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SDS-PAGE analysis of BMP8B (Human) Recombinant Protein.
Result of activity analysis
Result of activity analysis
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Specifications
Product Description
Human BMP8B recombinant protein with polyhistidine tag at the N-terminus expressed in Escherichia coli.
Sequence
AVRPLRRRQPKKSNELPQANRLPGIFDDVHGSHGRQVCRRHELYVSFQDLGWLDWVIAPQGYSAYYCEGECSFPLDSCMNATNHAILQSLVHLMMPDAVPKACCAPTKLSATSVLYYDSSNNVILRKHRNMVVKACGCH with polyhistidine tag at the N-terminus.
Host
Escherichia coli
Specificity
23
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purification
Ni-NTA chromatography
Purity
> 98% as determined by SDS-PAGE.
Endotoxin Level
< 0.01 EU/ ug of protein by the LAL method.
Quality Control Testing
SDS-PAGE Stained with Coomassie Blue.
SDS-PAGE analysis of BMP8B (Human) Recombinant Protein.
Recommend Usage
Biological Activity
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from a solution containing 20 mM sodium citrate, 0.2 M NaCl, pH 3.5. Reconstitute the lyophilized powder in ddH2O to a concentration not less than 100 ug/mL.
Storage Instruction
Lyophilized protein should be stored at -20°C. Protein aliquots should be stored at-20°C to -80°C. This product is stable for one year.
Avoid repeated freeze/thaw cycles.Note
Result of activity analysis
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Applications
Functional Study
SDS-PAGE
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Gene Info — BMP8B
Entrez GeneID
656Gene Name
BMP8B
Gene Alias
BMP8, MGC131757, OP2
Gene Description
bone morphogenetic protein 8b
Omim ID
602284Gene Ontology
HyperlinkGene Summary
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity. [provided by RefSeq
Other Designations
OTTHUMP00000010836|bone morphogenetic protein 8 (osteogenic protein 2)|bone morphogenetic protein 8B|dJ118J21.1 (bone morphogenetic protein 8 (osteogenic protein 2))|osteogenic protein 2
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Interactomes
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Pathways
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Diseases
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