FOLR1 (Human) Recombinant Protein
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Specification
Product Description
Human FOLR1 (NP_057936, 25 a.a. - 234 a.a ) partial recombinant protein with His tag expressed in Escherichia coli.
Sequence
MGSSHHHHHHSSGLVPRGSHMGSRIAWARTELLNVCMNAKHHKEKPGPEDKLHEQCRPWRKNACCSTNTSQEAHKDVSYLYRFNWNHCGEMAPACKRHFIQDTCLYECSPNLGPWIQQVDQSWRKERVLNVPLCKEDCEQWWEDCRTSYTCKSNWHKGWNWTSGFNKCAVGAACQPFHFYFPTPTVLCNEIWTHSYKVSNYSRGSGRCIQMWFDPAQGNPNEEVARFYAAAMS
Host
Escherichia coli
Theoretical MW (kDa)
27
Form
Liquid
Preparation Method
Escherichia coli expression system
Purity
> 85% by SDS-PAGE
Quality Control Testing
3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
SDS-PAGE analysis of FOLR1 (Human) Recombinant Protein
Recommend Usage
SDS-PAGE
Denatured
The optimal working dilution should be determined by the end user.Storage Buffer
In 20mM Tris-HCl buffer, pH8.0 (10% glycerol).
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
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Gene Info — FOLR1
Entrez GeneID
2348Protein Accession#
P15328Gene Name
FOLR1
Gene Alias
FBP, FOLR, FR-alpha, MOv18
Gene Description
folate receptor 1 (adult)
Omim ID
136430Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the folate receptor (FOLR) family. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This gene is composed of 7 exons; exons 1 through 4 encode the 5' UTR and exons 4 through 7 encode the open reading frame. Due to the presence of 2 promoters, multiple transcription start sites, and alternative splicing of exons, several transcript variants are derived from this gene. These variants differ in the lengths of 5' and 3' UTR, but they encode an identical amino acid sequence. [provided by RefSeq
Other Designations
folate binding protein|folate receptor 1
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Interactome
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