TRIB3 (Human) Recombinant Protein
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Specification
Product Description
Human TRIB3 (NP_066981, 1 a.a. - 358 a.a ) full-length recombinant protein with His tag expressed in Escherichia coli.
Sequence
MGSSHHHHHHSSGLVPRGSHMGSMRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPDRATAVATASRLGPYVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGDREVVLYG
Host
Escherichia coli
Theoretical MW (kDa)
42
Form
Liquid
Preparation Method
Escherichia coli expression system
Purity
> 85% by SDS-PAGE
Quality Control Testing
3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
SDS-PAGE analysis of TRIB3 (Human) Recombinant Protein
Recommend Usage
SDS-PAGE
Denatured
The optimal working dilution should be determined by the end user.Storage Buffer
In 20mM Tris-HCl buffer, pH8.0 (10% glycerol).
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
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Gene Info — TRIB3
Entrez GeneID
57761Protein Accession#
Q96RU7Gene Name
TRIB3
Gene Alias
C20orf97, NIPK, SINK, SKIP3, TRB3
Gene Description
tribbles homolog 3 (Drosophila)
Omim ID
607898Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. [provided by RefSeq
Other Designations
neuronal cell death inducible putative kinase|p65-interacting inhibitor of NF-kappaB|tribbles 3
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Interactome
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Disease
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