TNFSF18 (Human) Recombinant Protein
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Specification
Product Description
Human TNFSF18 (74 a.a. - 199 a.a.) partial recombinant protein with hFc tag at C-terminus expressed in HEK293 cells.
Host
Mammals
Theoretical MW (kDa)
50
Form
Lyophilized
Preparation Method
Mammalian cell (HEK293) expression system
Purity
> 95% by SDS-PAGE
Endotoxin Level
< 0.1 EU per 1 ug of protein (determined by gel clotting method)
Activity
Immobilized GITR, hFc, Human at 5.0 ug/mL (100 uL/well) can bind human biotinylated GITR Ligand, hFc, Human when detected by Streptavidin-HRP.
Storage Buffer
Lyophilized from sterile distilled Water up to 100 ug/mL
Storage Instruction
Store at 4°C to 8°C for 1 week. For long term storage store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — TNFSF18
Entrez GeneID
8995Gene Name
TNFSF18
Gene Alias
AITRL, GITRL, MGC138237, TL6, hGITRL
Gene Description
tumor necrosis factor (ligand) superfamily, member 18
Omim ID
603898Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq
Other Designations
AITR ligand|GITR ligand|glucocorticoid-induced TNFR-related protein ligand
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