ICOS (Human) Recombinant Protein
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Specification
Product Description
Human ICOS (Q9Y6W8, 21 a.a. - 141 a.a.) partial recombinant protein with hFc tag at C-terminus expressed in HEK293 cell.
Sequence
EINGSANYEMFIFHNGGVQILCKYPDIVQQFKMQLLKGGQILCDLTKTKGSGNTVSIKSLKFCHSQLSNNSVSFFLYNLDHSHANYYFCNLSIFDPPPFKVTLTGGYLHIYESQLCCQLKF
Host
Mammals
Theoretical MW (kDa)
50.5
Form
Lyophilized
Preparation Method
Mammalian cell (HEK293) expression system
Purity
> 90% by SDS-PAGE
Endotoxin Level
< 0.2 EU per 1 ug of protein (determined by gel clotting method)
Storage Buffer
Lyophilized from sterile distilled Water up to 100 ug/mL
Storage Instruction
Store at 4°C to 8°C for 1 week. For long term storage store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — ICOS
Entrez GeneID
29851Protein Accession#
Q9Y6W8Gene Name
ICOS
Gene Alias
AILIM, CD278, MGC39850
Gene Description
inducible T-cell co-stimulator
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. [provided by RefSeq
Other Designations
activation-inducible lymphocyte immunomediatory molecule|inducible costimulator
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Interactome
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Pathway
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Disease
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