CXCL5 (Human) Recombinant Protein
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Specification
Product Description
Human CXCL5 (P42830, 37 a.a. - 114 a.a.) partial recombinant protein expressed in HEK293 cells.
Sequence
AGPAAAVLRELRCVCLQTTQGVHPKMISNLQVFAIGPQCSKVEVVASLKNGKEICLDPEAPFLKKVIQKILDGGNKEN
Host
Human
Theoretical MW (kDa)
~ 8.5
Form
Lyophilized
Preparation Method
_x005F_x000D__x000D_ Mammalian cell (HEK 293) expression system_x005F_x000D__x000D_
Purity
> 98% as analyzed by SDS-PAGE.
Endotoxin Level
< 0.2 EU/ ug of protein (gel clotting method)
Activity
Human CXCL5 EC50 < 200 ng/mL, measured on Ca2+ mobilization assay in CHO-K1/ Galpha15/hCXCR2 cells (human Galpha15 and human CXCR2 stably expressed in CHO-K1 cells).
Recommend Usage
Biological Activity
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from PBS. Reconstitute the lyophilized powder in ddH2O up to 100 ug/mL.
Storage Instruction
Store at 4°C for 1 week. For long term storage store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — CXCL5
Entrez GeneID
6374Protein Accession#
P42830Gene Name
CXCL5
Gene Alias
ENA-78, SCYB5
Gene Description
chemokine (C-X-C motif) ligand 5
Omim ID
600324Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an inflammatory chemokine that belongs to the CXC chemokine family. This chemokine is produced concomitantly with interleukin-8 (IL8) in response to stimulation with either interleukin-1 (IL1) or tumor necrosis factor-alpha (TNFA). This chemokine is a potent chemotaxin involved in neutrophil activation. [provided by RefSeq
Other Designations
epithelial-derived neutrophil activating protein 78|epithelial-derived neutrophil-activating peptide 78|neutrophil-activating peptide ENA-78|neutrophil-activating protein 78|small inducible cytokine B5|small inducible cytokine subfamily B (Cys-X-Cys), mem
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Interactome
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Disease
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