AREG (Human) Recombinant Protein

Catalog # P7362

Size

Price

Stock

Quantity

Size:10 ug
Price: USD $ 109.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
  • Specification

    Product Description

    Human AREG (P15514, 101 a.a. - 198 a.a ) partial recombinant protein expressed in HEK293 cells.Bioactive Protein,Bioactive Proteins,Bioactive,Active,Functional Protein,Functional Proteins,Recombinant Human Protein,Recombinant Human Proteins,Human Recombinant Protein,Human Recombinant Proteins,HuPro

    Sequence

    SVRVEQVVKPPQNKTESENTSDKPKRKKKGGKNGKNRRNRKKKNPCNAEFQNFCIHGECKYIEHLEAVTCKCQQEYFGERCGEKSMKTHSMIDSSLSK

    Host

    Human

    Theoretical MW (kDa)

    15 - 20

    Form

    Lyophilized

    Preparation Method

    Mammalian cell (HEK 293) expression system

    Purity

    > 95% as analyzed by SDS-PAGE.

    Endotoxin Level

    < 0.2 EU/ug of protein by gel clotting method

    Activity

    ED50 < 0.2 ng/ml, measured in a cell proliferation assay using 3T3 cells.

    Recommend Usage

    Biological Activity
    SDS-PAGE
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    Lyophilized from PBS. Reconstitute the lyophilized powder in ddH2O up to 100 ug/mL.

    Storage Instruction

    Store at 4°C to 8°C for 1 week. For long term storage store at -20°C to -80°C.
    Aliquot to avoid repeated freezing and thawing.

  • Applications

    Functional Study

    SDS-PAGE

  • Gene Info — AREG

    Entrez GeneID

    374

    Protein Accession#

    P15514

    Gene Name

    AREG

    Gene Alias

    AR, CRDGF, MGC13647, SDGF

    Gene Description

    amphiregulin

    Omim ID

    104640

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This encoded protein is associated with a psoriasis-like skin phenotype. [provided by RefSeq

    Other Designations

    OTTHUMP00000160473|colorectum cell-derived growth factor|schwannoma-derived growth factor

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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