APOE2 (Human) Recombinant Protein
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Specification
Product Description
Human APOE2 (NP_000032.1) recombinant protein expressed in Escherichia coli.
Host
Escherichia coli
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
>= 90% by SDS-PAGE and HPLC
Endotoxin Level
< 0.1 ng/ug
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
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Gene Info — APOE
Entrez GeneID
348Protein Accession#
NP_000032.1Gene Name
APOE
Gene Alias
AD2, LPG, MGC1571, apoprotein
Gene Description
apolipoprotein E
Gene Ontology
HyperlinkGene Summary
Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq
Other Designations
apolipoprotein E3
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Interactome
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Disease
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