DEFB1 (Human) Recombinant Protein
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Specification
Product Description
Human DEFB1 (P60022, 22 a.a. - 68 a.a.) partial recombinant protein expressed in Escherichia coli.
Sequence
GNFLTGLGHRSDHYNCVSSGGQCLYSACPIFTKIQGTCYRGKAKCCK
Host
Escherichia coli
Theoretical MW (kDa)
5.1
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
> 98% by SDS-PAGE
Endotoxin Level
< 1 EU per 1 ug of protein (determined by LAL method)
Activity
The biological activity determined by a chemotaxis bioassay using CD34+ dendritic cells is in a concentration range of 100.0 - 1000.0 ng/ml.
Storage Buffer
Lyophilized from sterile distilled Water up to 0.1 - 1.0 mg/ml
Storage Instruction
Store at 4°C to 8°C for 1 week. For long term storage store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — DEFB1
Entrez GeneID
1672Protein Accession#
P60022Gene Name
DEFB1
Gene Alias
BD1, DEFB-1, DEFB101, HBD1, MGC51822
Gene Description
defensin, beta 1
Omim ID
602056Gene Ontology
HyperlinkGene Summary
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. [provided by RefSeq
Other Designations
beta-defensin-1
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Interactome
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Disease
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