FURIN (Human) Recombinant Protein
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Human FURIN (108 a.a. - 715 a.a.) partial recombinant protein with His tag expressed in HEK293 cells.
Theoretical MW (kDa)
66
Form
Lyophilized
Preparation Method
Mammalian cell (HEK293) expression system
Purity
≥ 95% by SDS-PAGE
Endotoxin Level
< 1 EU/μg
Activity
The specific activity is > 150 pMole/min/ug
Recommend Usage
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (5% Trehalose), pH 7.2.
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
-
Gene Info — FURIN
Entrez GeneID
5045Protein Accession#
P09958Gene Name
FURIN
Gene Alias
FUR, PACE, PCSK3, SPC1
Gene Description
furin (paired basic amino acid cleaving enzyme)
Omim ID
136950Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can efficiently cleave precursor proteins at their paired basic amino acid processing sites. Some of its substrates are: proparathyroid hormone, transforming growth factor beta 1 precursor, proalbumin, pro-beta-secretase, membrane type-1 matrix metalloproteinase, beta subunit of pro-nerve growth factor and von Willebrand factor. It is also thought to be one of the proteases responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene is thought to play a role in tumor progression. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq
Other Designations
FES upstream region|dibasic processing enzyme|furin|furin, membrane associated receptor protein|paired basic amino acid cleaving enzyme (furin, membrane associated receptor protein)|proprotein convertase subtilisin/kexin type 3
-
Interactome
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com