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Last updated: 2022/5/22

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FOLR2 (Human) Recombinant Protein BioActive

  • Catalog # : P6986
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  • Specification
  • Product Description:
  • Human FOLR2 (NP_000794.3, 22 a.a.- 230 a.a.) partial recombinant protein with C-terminal His tag expressed in HEK293 cells.
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 25.1
  • Form:
  • Liquid
  • Preparation Method:
  • Mammalian cell (HEK293) expression system
  • Purity:
  • > 90% by SDS-PAGE
  • Endotoxin Level:
  • < 1 EU per 1 ug of protein (determined by LAL method).
  • Activity:
  • Measured by its binding ability in a functional ELISA with Folic Acid-BSA. The ED50 range ≤ 5 ug/mL.
  • Quality Control Testing:
  • 3 ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

    QC Testing of P6986
  • Recommend Usage:
  • Bioactivity
    SDS-PAGE
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (10% glycerol).
  • Storage Instruction:
  • Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Result of bioactivity analysis
  • Folic Acid-BSA is coated at 10 ug/mL (100 uL/well) can bind FOLR2 (Human) Recombinant Protein (Cat # P6986). The ED50 range ≤ 5 ug/mL.


  • Applications
  • SDS-PAGE
  • Application Image
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 2350
  • Gene Name:
  • FOLR2
  • Gene Alias:
  • BETA-HFR,FBP/PL-1,FR-BETA,FR-P3
  • Gene Description:
  • folate receptor 2 (fetal)
  • Gene Summary:
  • The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq
  • Other Designations:
  • folate receptor 2,folate receptor, beta,folate-binding protein, fetal/placental
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