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Last updated: 2022/5/22

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NQO1 (Human) Recombinant Protein BioActive

  • Catalog # : P6969
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  • Specification
  • Product Description:
  • Human NQO1 (NP_000894, 1 a.a. - 274 a.a.) full length recombinant protein with His tag expressed in Escherichia coli.
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 33
  • Form:
  • Liquid
  • Preparation Method:
  • Escherichia coli expression system
  • Purity:
  • > 95% by SDS-PAGE
  • Endotoxin Level:
  • > 1 EU per 1ug of protein (determined by LAL method)
  • Activity:
  • Specific activity is > 1,000 pmol/min/ug and is defined as the amount of enzyme that converts 1 pmole of resazurin to resorufin per minute at pH 7.5 at 25°C.
  • Quality Control Testing:
  • 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

    QC Testing of P6969
  • Recommend Usage:
  • SDS-PAGE
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 20mM Tris-HCl, pH 8.0 (1 mM DTT, 10% glycerol)
  • Storage Instruction:
  • Stored at 2°C to 8°C for 1 week.
    For long term storage, aliquot and store at -20°C to -80°C.
    Avoid repeated freezing and thawing cycles.
  • Applications
  • SDS-PAGE
  • Application Image
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 1728
  • Gene Name:
  • NQO1
  • Gene Alias:
  • DHQU,DIA4,DTD,NMOR1,NMORI,QR1
  • Gene Description:
  • NAD(P)H dehydrogenase, quinone 1
  • Gene Summary:
  • This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
  • Other Designations:
  • DT-diaphorase,NAD(P)H menadione oxidoreductase 1, dioxin-inducible,NAD(P)H:Quinone acceptor oxidoreductase type 1,NAD(P)H:menadione oxidoreductase 1,NAD(P)H:quinone oxireductase,azoreductase,diaphorase (NADH/NADPH) (cytochrome b-5 reductase),diaphorase-4,
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