NME1 (Human) Recombinant Protein

Catalog # P6938

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Price

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Quantity

Size:100 ug
Price: USD $ 428.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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QC Test

3 ug SDS-PAGE under reducing condition and visualized by coomassie blue stain.

  • Specification

    Product Description

    Human NME1 (NP_000260, 1 - 152 a.a.) full length recombinant protein expressed in Escherichia coli expression system.Bioactive Protein,Bioactive Proteins,Bioactive,Active,Functional Protein,Functional Proteins,Full-Length Protein,Full-Length Proteins,Full-Length,Full Length,FullLength

    Host

    Escherichia coli

    Theoretical MW (kDa)

    17.1

    Form

    Liquid

    Preparation Method

    Escherichia coli expression system

    Purity

    > 90% by SDS-PAGE

    Endotoxin Level

    < 1 EU/ug

    Activity

    Specific activity is > 1,200 units/mg, and is defined as the amount of enzyme that convert 1.0 umole each of ATP and TDP to ADP and TTP per minute at pH 7.5 at 25°C in a couple system with PK/LDH.

    Quality Control Testing

    SDS-PAGE Stained with Coomassie Blue

    3 ug SDS-PAGE under reducing condition and visualized by coomassie blue stain.

    Recommend Usage

    SDS-PAGE
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In 20 mM Tris-HCl, 1 mM DTT, pH 7.5 (10% glycerol)

    Storage Instruction

    Store at 4°C for one week. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

  • Applications

    SDS-PAGE

  • Gene Info — NME1

    Entrez GeneID

    4830

    Protein Accession#

    P15531

    Gene Name

    NME1

    Gene Alias

    AWD, GAAD, NB, NBS, NDPK-A, NDPKA, NM23, NM23-H1

    Gene Description

    non-metastatic cells 1, protein (NM23A) expressed in

    Omim ID

    156490 256700

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq

    Other Designations

    NDP kinase A|OTTHUMP00000174772

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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