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Last updated: 2022/10/2

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ACHE (Human) Recombinant Protein 

  • Catalog # : P6925
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  • Specification
  • Product Description:
  • Human ACHE (P22303, 32 a.a. - 614 a.a.) partial recombinant protein with 6x His tag at C-terminal expressed in HEK293 cells.
  • Host:
  • Human
  • Theoretical MW (kDa):
  • ~70
  • Form:
  • Lyophilized
  • Preparation Method:
  • Mammalian cell (HEK293) expression system
  • Purity:
  • > 95% by SDS-PAGE
  • Quality Control Testing:
  • Loading 2 ug protein in 4-20% SDS-PAGE

    QC Testing of P6925
    Lane 1: reducing (monomer).
    Lane 2: non-reducing conditions.
  • Recommend Usage:
  • SDS-PAGE
    The optimal working dilution should be determined by the end user.
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • SDS-PAGE
  • Enzyme Activity
  • Application Image
  • SDS-PAGE
  • Enzyme Activity
  • Gene Information
  • Entrez GeneID:
  • 43
  • Gene Name:
  • ACHE
  • Gene Alias:
  • ARACHE,N-ACHE,YT
  • Gene Description:
  • acetylcholinesterase (Yt blood group)
  • Gene Summary:
  • Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. [provided by RefSeq
  • Other Designations:
  • acetylcholinesterase,apoptosis-related acetylcholinesterase
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