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Last updated: 2022/5/22

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PRNP (Human) Recombinant Protein BioActive

  • Catalog # : P6910
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  • Specification
  • Product Description:
  • Human PRNP (P06873) recombinant protein expressed in Tritirachium album expression system
  • Host:
  • Human
  • Form:
  • Liquid
  • Preparation Method:
  • Tritirachium album expression system
  • Purity:
  • > 90% by SDS-PAGE
  • Activity:
  • Specific activity is > 30 units/mg.
  • Storage Instruction:
  • Store at -20°C for 12 months.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Enzyme Activity
  • Application Image
  • Enzyme Activity
  • Gene Information
  • Entrez GeneID:
  • 5621
  • Gene Name:
  • PRNP
  • Gene Alias:
  • ASCR,CD230,CJD,GSS,MGC26679,PRIP,PrP,PrP27-30,PrP33-35C,PrPc,prion
  • Gene Description:
  • prion protein
  • Gene Summary:
  • The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
  • Other Designations:
  • CD230 antigen,OTTHUMP00000030162,OTTHUMP00000030163,major prion protein,p27-30,prion protein PrP,prion-related protein
  • Gene Pathway
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