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Last updated: 2022/7/3

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BACE1 (Human) Recombinant Protein BioActive

  • Catalog # : P6888
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  • Specification
  • Product Description:
  • Human BACE1 (P56817, 46 a.a - 460 a.a.) partial recombinant protein expressed in insect cell expression system.
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 47
  • Form:
  • Liquid
  • Preparation Method:
  • Insect cell expression system
  • Purity:
  • > 90% by SDS-PAGE
  • Activity:
  • Specific activity is ≥ 10 mU/mg.
  • Quality Control Testing:
  • SDS-PAGE Stained with Coomassie Blue

    QC Testing of P6888
    BACE1 (Human) Recombinant Protein (Cat # P6888) was determined by SDS-PAGE, showing a band at 48 kDa.
  • Recommend Usage:
  • SDS-PAGE
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (50% glycerol)
  • Storage Instruction:
  • Store at -80°C for 12 months.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • SDS-PAGE
  • Enzyme Activity
  • Application Image
  • SDS-PAGE
  • Enzyme Activity
  • Gene Information
  • Gene Name:
  • BACE1
  • Gene Alias:
  • ASP2,BACE,FLJ90568,HSPC104,KIAA1149
  • Gene Description:
  • beta-site APP-cleaving enzyme 1
  • Gene Summary:
  • Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
  • Other Designations:
  • APP beta-secretase,aspartyl protease 2,beta-secretase,beta-site amyloid beta A4 precursor protein-cleaving enzyme,beta-site amyloid precursor protein cleaving enzyme,memapsin-2,membrane-associated aspartic protease 2,transmembrane aspartic proteinase Asp2
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