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Last updated: 2022/5/22

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CES1 (Human) Recombinant Protein BioActive

  • Catalog # : P6834
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  • Specification
  • Product Description:
  • Human Carboxylesterase 1/CES1 protein (NP_001020366, 19 a.a.-568 a.a.) partial recombinant protein with His tag expressed in Baculovirus expression system.
  • Host:
  • Viruses
  • Theoretical MW (kDa):
  • 61.7
  • Form:
  • Liquid
  • Preparation Method:
  • Baculovirus expression system
  • Purity:
  • > 90% by SDS-PAGE
  • Endotoxin Level:
  • < 1 EU/ug
  • Activity:
  • Specific activity is > 700 pmol/min/ug and is defined as the amount of enzyme that hydrolyze 1pmole of p-nitrophenyl acetate to pnitrophenol per minute at pH 7.5 at 37°C.
  • Quality Control Testing:
  • 15% SDS-PAGE under reducing condition and visualized by coomassie blue stain.

    QC Testing of P6834
    15% SDS-PAGE under reducing condition and visualized by coomassie blue stain.
  • Recommend Usage:
  • SDS-PAGE
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 25 mM Sodium Acetate, 0.1 M NaCl, pH 4.0 (10% glycerol, 0.1 mM PMSF)
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • SDS-PAGE
  • Application Image
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 1066
  • Gene Name:
  • CES1
  • Gene Alias:
  • ACAT,CEH,CES2,HMSE,HMSE1,MGC117365,PCE-1,SES1,TGH
  • Gene Description:
  • carboxylesterase 1 (monocyte/macrophage serine esterase 1)
  • Gene Summary:
  • Carboxylesterase 1 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Carboxylesterase deficiency may be associated with non-Hodgkin lymphoma or B-cell lymphocytic leukemia. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • acyl coenzyme A:cholesterol acyltransferase,carboxylesterase 1,carboxylesterase 2 (liver),cholesteryl ester hydrolase,egasyn,liver carboxylesterase,triacylglycerol hydrolase
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