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Last updated: 2022/5/15

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HK2 (Human) Recombinant Protein BioActive

  • Catalog # : P6830
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  • Specification
  • Product Description:
  • Human Hexokinase 2 protein (NP_000180, 1 a.a.-917 a.a.) full length recombinant protein with His tag expressed in Escherichia coli.
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 104.5
  • Form:
  • Liquid
  • Preparation Method:
  • Escherichia coli expression system
  • Purity:
  • > 90% by SDS-PAGE
  • Endotoxin Level:
  • < 1 EU/ug
  • Activity:
  • Specific activity is > 40000 pmol/min/ug. One unit will convert 1 pmole of D-Glucose to D-Glucose-6-phosphate per minute at pH8.0 at 37°C.
  • Quality Control Testing:
  • 15% SDS-PAGE under reducing condition and visualized by coomassie blue stain.

    QC Testing of P6830
    15% SDS-PAGE under reducing condition and visualized by coomassie blue stain.
  • Recommend Usage:
  • SDS-PAGE
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 20 mM Tris-HCl, 0.1 M NaCl, pH 8.0 (10% glycerol, 0.1 mM PMSF)
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • SDS-PAGE
  • Application Image
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 3099
  • Gene Name:
  • HK2
  • Gene Alias:
  • DKFZp686M1669,HKII,HXK2
  • Gene Description:
  • hexokinase 2
  • Gene Summary:
  • Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. [provided by RefSeq
  • Other Designations:
  • hexokinase-2, muscle
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