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Last updated: 2022/5/22

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GNMT (Human) Recombinant Protein BioActive

  • Catalog # : P6825
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  • Specification
  • Product Description:
  • Human Glycine N-methyltransferase/GNMT protein (NP_061833, 1 a.a.-295 a.a.) full length recombinant protein with His tag expressed in Escherichia coli.
  • Host:
  • Escherichia coli
  • Theoretical MW (kDa):
  • 34.9
  • Form:
  • Liquid
  • Preparation Method:
  • Escherichia coli expression system
  • Purity:
  • > 95% by SDS-PAGE
  • Endotoxin Level:
  • < 1 EU/ug
  • Activity:
  • Specific activity is > 100 nmol/min/mg, and is defined as the amount of enzyme that transfer 1.0 nmole of methyl group per minute at 37°C.
  • Quality Control Testing:
  • SDS-PAGE under reducing condition and visualized by coomassie blue stain.

    QC Testing of P6825
    SDS-PAGE under reducing condition and visualized by coomassie blue stain.
  • Recommend Usage:
  • SDS-PAGE
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 20 mM Tris-HCl, pH 8.0 (20% glycerol)
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • SDS-PAGE
  • Application Image
  • SDS-PAGE
  • Gene Information
  • Gene Name:
  • GNMT
  • Gene Alias:
  • -
  • Gene Description:
  • glycine N-methyltransferase
  • Gene Summary:
  • The protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. The encoded protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia). [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000016412
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