AKR1C4 (Human) Recombinant Protein

Catalog # P6808

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Price

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Quantity

Size:20 ug
Price: USD $ 140.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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QC Test

15% SDS-PAGE Stained with Coomassie Blue.

  • Specification

    Product Description

    Human AKR1C4 (NP_001809, 1 a.a. - 323 a.a.) full length recombinant protein expressed in Escherichia coli.Bioactive Protein,Bioactive Proteins,Bioactive,Active,Functional Protein,Functional Proteins,Full-Length Protein,Full-Length Proteins,Full-Length,Full Length,FullLength

    Host

    Escherichia coli

    Theoretical MW (kDa)

    37

    Form

    Liquid

    Preparation Method

    Escherichia coli expression system

    Purity

    > 90% by SDS-PAGE

    Endotoxin Level

    < 1 EU/ug

    Activity

    Specific activity is > 700 pmol/min/ug, and is defined as the amount of enzyme that catalyze the oxidation of 1.0 pmole 1-Acenaphthenol in the presence of NADP per minute at pH 8.8 at 25°C.

    Quality Control Testing

    SDS-PAGE Stained with Coomassie Blue

    15% SDS-PAGE Stained with Coomassie Blue.

    Recommend Usage

    SDS-PAGE
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In 20 mM Tris-HCl, 0.1 M NaCl, 1 mM DTT, pH 8.5 (10% glycerol)

    Storage Instruction

    Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.

  • Applications

    SDS-PAGE

  • Gene Info — AKR1C4

    Entrez GeneID

    1109

    Protein Accession#

    P17516

    Gene Name

    AKR1C4

    Gene Alias

    3-alpha-HSD, C11, CDR, CHDR, DD4, HAKRA, MGC22581

    Gene Description

    aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)

    Omim ID

    600451

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq

    Other Designations

    3 alpha-hydroxysteroid dehydrogenase/dihydrodiol dehydrogenase 4|OTTHUMP00000018997|aldo-keto reductase family 1, member C4|chlordecone reductase|dihydrodiol dehydrogenase 4|dihydrodiol dehydrogenase isozyme DD4|type I 3-alpha-hydroxysteroid dehydrogenase

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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