CD244 (Human) Recombinant Protein

Catalog # P6780

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Price

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Quantity

Size:100 ug
Price: USD $ 407.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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QC Test

CD244 (Human) Recombinant Protein (Cat # P6780) was determined by SDS-PAGE with Coomassie Blue, showing a band at 70-90 kDa.

Result of activity analysis
Note

Result of activity analysis

Result of activity analysis

  • Specification

    Product Description

    Human CD244 (NP_057466.1, 22 a.a. - 221 a.a.) partial recombinant protein with Fc, 6x His tag at C-terminal expressed in HEK293 cells.Bioactive Protein,Bioactive Proteins,Bioactive,Active,Functional Protein,Functional Proteins,Recombinant Human Protein,Recombinant Human Proteins,Human Recombinant Protein,Human Recombinant Proteins,HuPro

    Host

    Human

    Form

    Lyophilized

    Preparation Method

    Mammalian cell (HEK293) expression system

    Purification

    Ni-sepharose purification

    Purity

    > 95% by SDS-PAGE

    Endotoxin Level

    < 0.1 EU/ug of the protein by LAL method.

    Activity

    Measured by the binding ability in a functional ELISA. Immobilized recombinant human CD48 at 5 ug/mL (100 uL/well) can bind CD244 (Human) Recombinant Protein (Cat # P6780) with a linear range of 0.2-1 ug/mL.

    Quality Control Testing

    SDS-PAGE Stained with Coomassie Blue

    CD244 (Human) Recombinant Protein (Cat # P6780) was determined by SDS-PAGE with Coomassie Blue, showing a band at 70-90 kDa.

    Recommend Usage

    SDS-PAGE
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    Lyophilized from PBS, pH 7.4.

    Storage Instruction

    Store the lyophilized protein at -20°C to -80°C for long term.
    After reconstitution to a concentration of 0.1-0.5 mg/mL in sterile distilled water, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
    Aliquot to avoid repeated freezing and thawing.

    Note

    Result of activity analysis

  • Applications

    SDS-PAGE

  • Gene Info — CD244

    Entrez GeneID

    51744

    Protein Accession#

    NP_057466.1

    Gene Name

    CD244

    Gene Alias

    2B4, NAIL, NKR2B4, Nmrk, SLAMF4

    Gene Description

    CD244 molecule, natural killer cell receptor 2B4

    Omim ID

    605554

    Gene Ontology

    Hyperlink

    Gene Summary

    Natural killer (NK) cells express both activating and inhibitory cell surface receptors. Inhibitory signaling receptors all possess cytoplasmic immunoreceptor tyrosine-based inhibitory motifs, or ITIMs, whereas the activating receptors lack ITIMs and associate with DAP12 (TYROBP; MIM 604142), which contains an immunoreceptor tyrosine-based activation motif, or ITAM. Killer cell immunoglobulin (Ig)-like receptors, or KIRs (see KIR2DL1; MIM 604936), and other NK cell receptors interact with major histocompatibility complex (MHC) molecules (see MIM 142800). Members of the CD2 (MIM 186990) family adhere to each other instead. The cell surface glycoprotein 2B4 is related to CD2 and is implicated in the regulation of NK- and T-cell function (Boles et al., 1999 [PubMed 10458320]).[supplied by OMIM

    Other Designations

    CD244 natural killer cell receptor 2B4|NK cell activation inducing ligand NAIL|OTTHUMP00000027884|natural killer cell receptor 2B4

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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