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Last updated: 2022/5/22

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ICOS (Human) Recombinant Protein BioActive

  • Catalog # : P6778
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  • Specification
  • Product Description:
  • Human ICOS (Q9Y6W8, 21 a.a. - 141 a.a.) partial recombinant protein with hFc tag at C-terminal expressed in Expi293 cells.
  • Host:
  • Human
  • Form:
  • Lyophilized
  • Preparation Method:
  • Mammalian cell (Expi293) expression system
  • Purification:
  • Protein A purification
  • Purity:
  • > 95% by Tris-Bis PAGE
  • Endotoxin Level:
  • < 1.0 EU/ug of the protein by LAL method.
  • Activity:
  • Immobilized Human B7-H2, His (BH7-HM472) at 0.5 ug/mL (100 uL/Well) on the plate. Dose response curve for ICOS (Human) Recombinant Protein (Cat # P6778), hFc with the ED50 of 45.6 ng/mL determined by ELISA.
  • Quality Control Testing:
  • Tris-Bis PAGE with Coomassie Blue

    QC Testing of P6778
    ICOS (Human) Recombinant Protein (Cat # P6778) on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
  • Recommend Usage:
  • Tris-Bis PAGE
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from PBS, pH 7.4.
  • Storage Instruction:
  • Store the lyophilized protein at -20°C to -80°C for long term.
    After reconstitution to a concentration of 0.1-0.5 mg/mL in sterile distilled water, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Result of activity analysis

  • Applications
  • Immunogen
  • SDS-PAGE
  • Application Image
  • Immunogen
  • SDS-PAGE
  • Gene Information
  • Gene Name:
  • ICOS
  • Gene Alias:
  • AILIM,CD278,MGC39850
  • Gene Description:
  • inducible T-cell co-stimulator
  • Gene Summary:
  • The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. [provided by RefSeq
  • Other Designations:
  • activation-inducible lymphocyte immunomediatory molecule,inducible costimulator
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