CEACAM6 (Human) Recombinant Protein
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Specification
Product Description
Human CEACAM6 (NP_002474.3, 35 a.a. - 320 a.a.) partial recombinant protein with His tag at C-terminus expressed in HEK293 cells.
Host
Human
Theoretical MW (kDa)
45-65
Form
Lyophilized
Preparation Method
Mammalian cell (HEK293) expression system
Purification
Ni-sepharose purification
Purity
> 95% by SDS-PAGE
Endotoxin Level
< 0.1 EU/ug
Activity
Measured by the binding ability in a functional ELISA. Immobilized Recombinant Human CEACAM6 at 2 ug/mL (100 uL/well) can bind Recombinant Human CEACAM8 with a linear range of 0.1-0.4 ug/mL.
Quality Control Testing
SDS-PAGE Stained with Coomassie Blue
CEACAM6 (Human) Recombinant Protein (Cat #P6773) was determined by SDS-PAGE with Coomassie Blue, showing a band at 45-65 kDa.
Recommend Usage
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from PBS, pH 7.4.
Storage Instruction
Store the lyophilized protein at -20°C to -80°C for long term.
After reconstitution to a concentration of 0.1-0.5 mg/mL in sterile distilled water, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
Aliquot to avoid repeated freezing and thawing.Note
Result of activity analysis
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Applications
SDS-PAGE
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Gene Info — CEACAM6
Entrez GeneID
4680Protein Accession#
P40199Gene Name
CEACAM6
Gene Alias
CD66c, CEAL, NCA
Gene Description
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
Omim ID
163980Gene Ontology
HyperlinkGene Summary
Carcinoembryonic antigen (CEA; MIM 114890) is one of the most widely used tumor markers in serum immunoassay determinations of carcinoma. An apparent lack of absolute cancer specificity for CEA probably results in part from the presence in normal and neoplastic tissues of antigens that share antigenic determinants with the 180-kD form of CEA (Barnett et al., 1988 [PubMed 3220478]). For background information on the CEA family of genes, see CEACAM1 (MIM 109770).[supplied by OMIM
Other Designations
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Interactome
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Disease
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