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Last updated: 2022/5/22

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TNFRSF8 (Human) Recombinant Protein BioActive

  • Catalog # : P6749
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  • Specification
  • Product Description:
  • Human TNFRSF8 (NP_001234.2, 19 a.a. - 379 a.a.) partial recombinant protein with a 6×His tag at the C-terminus expressed in HEK293 cells
  • Host:
  • Human
  • Form:
  • Lyophilized
  • Preparation Method:
  • Mammalian cell (HEK293) expression system
  • Purification:
  • Ni-sepharose purification
  • Purity:
  • > 97% (determined by SDS-PAGE)
  • Endotoxin Level:
  • < 0.1 EU/ug of protein (determined by LAL method)
  • Activity:
  • Measured by its binding ability in a functional ELISA. Immobilized recombinant human TNFRSF8 at 2 ug/mL (100 uL/well) can bind recombinant human TNFSF8 with a linear range of 1.22-15.23 ng/mL.
  • Quality Control Testing:
  • SDS-PAGE Stained with Coomassie Blue

    QC Testing of P6749
  • Recommend Usage:
  • SDS-PAGE
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from a 0.22 um filtered solution of PBS, pH 7.4.
  • Storage Instruction:
  • Store at -80°C on dry atmosphere, lyophilized antibodies are stable at least 2 years.
    After reconstitution with deionized water, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Result of activity analysis

  • Applications
  • Immunogen
  • SDS-PAGE
  • Application Image
  • Immunogen
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 943
  • Gene Name:
  • TNFRSF8
  • Gene Alias:
  • CD30,D1S166E,KI-1
  • Gene Description:
  • tumor necrosis factor receptor superfamily, member 8
  • Gene Summary:
  • The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
  • Other Designations:
  • CD30 antigen,CD30L receptor,Ki-1 antigen,OTTHUMP00000001783,cytokine receptor CD30,lymphocyte activation antigen CD30
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