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Last updated: 2022/5/22

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CD27 (Human) Recombinant Protein BioActive

  • Catalog # : P6744
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  • Specification
  • Product Description:
  • Human CD27 (21 a.a. - 192 a.a.) partial recombinant protein with a hFc tag at the C-terminus expressed in Expi293 cells.
  • Host:
  • Human
  • Form:
  • Lyophilized
  • Preparation Method:
  • Mammalian cell (Expi293) expression system
  • Purification:
  • Protein A purification
  • Purity:
  • > 95% (determined by Tris-Bis PAGE)
  • Endotoxin Level:
  • < 1 EU/ug of protein (determined by LAL method)
  • Activity:
  • Immobilized human CD27L, His tag at 1 ug/mL (100 uL/well). Dose response curve for Human CD27, Fc tag with the EC50 of 0.6 ug/mL determined by ELISA.
  • Quality Control Testing:
  • Tris-Bis PAGE under reduced condition.

    QC Testing of P6744
  • Recommend Usage:
  • Tris-Bis PAGE
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from a 0.22 um filtered solution of PBS, pH 7.4.
  • Storage Instruction:
  • Store at -80°C on dry atmosphere, lyophilized antibodies are stable at least 2 years.
    After reconstitution with deionized water, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Result of activity analysis

  • Applications
  • Immunogen
  • SDS-PAGE
  • Application Image
  • Immunogen
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 939
  • Gene Name:
  • CD27
  • Gene Alias:
  • MGC20393,S152,T14,TNFRSF7,Tp55
  • Gene Description:
  • CD27 molecule
  • Gene Summary:
  • The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq
  • Other Designations:
  • CD27 antigen,CD27L receptor,T cell activation antigen CD27,T cell antivation antigen S152,tumor necrosis factor receptor superfamily, member 7
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