CD3E/CD3G (Human) Recombinant Protein
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Result of activity analysis
Result of activity analysis
-
Specification
Product Description
Human CD3E/CD3G (P07766, 23 a.a. - 126 a.a./P09693, 23 a.a. - 116 a.a.) partial recombinant protein with a Fc, Avi tag at the C-terminus expressed in mammalian cells.
Host
Human
Form
Lyophilized
Preparation Method
Mammalian cell expression system
Purification
Protein A purification
Purity
> 95% (determined by Tris-Bis PAGE)
Endotoxin Level
< 0.1 EU/ug of protein (determined by LAL method)
Activity
Immobilized biotinylated human CD3E/CD3G, Fc tag at 0.5 ug/mL (100 uL/well) on streptavidin precoated (0.2 ug/mL) plate. Dose response curve for Anti-CD3 Ab with the EC50 of 22.4 ng/mL determined by ELISA.
Quality Control Testing
Tris-Bis PAGE under reduced condition.
Recommend Usage
Tris-Bis PAGE
The optimal working dilution should be determined by the end user.Conformation
Heterodimer
Storage Buffer
Lyophilized from a 0.22 um filtered solution of 20 mM PB, pH 7.4 (5% Trehalose).
Storage Instruction
Store at -80°C on dry atmosphere, lyophilized antibodies are stable at least 2 years.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.Note
Result of activity analysis
-
Applications
SDS-PAGE
-
Gene Info — CD3E
Entrez GeneID
916Protein Accession#
P07766;P09693Gene Name
CD3E
Gene Alias
FLJ18683, T3E, TCRE
Gene Description
CD3e molecule, epsilon (CD3-TCR complex)
Omim ID
186830Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq
Other Designations
CD3-epsilon|CD3E antigen, epsilon polypeptide|CD3e antigen, epsilon polypeptide (TiT3 complex)|T-cell antigen receptor complex, epsilon subunit of T3|T-cell surface antigen T3/Leu-4 epsilon chain|T-cell surface glycoprotein CD3 epsilon chain
-
Gene Info — CD3G
Entrez GeneID
917Protein Accession#
P07766;P09693Gene Name
CD3G
Gene Alias
CD3-GAMMA, FLJ17620, FLJ17664, FLJ79544, FLJ94613, MGC138597, T3G
Gene Description
CD3g molecule, gamma (CD3-TCR complex)
Omim ID
186740Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency. [provided by RefSeq
Other Designations
CD3G antigen, gamma polypeptide|CD3g antigen, gamma polypeptide (TiT3 complex)|T-cell antigen receptor complex, gamma subunit of T3|T-cell receptor T3 gamma chain|T-cell surface glycoprotein CD3 gamma chain
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com